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João Lobo Selected Research

Testicular Germ Cell Tumor

10/2021Combining Hypermethylated RASSF1A Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients.
1/2021Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest.
1/2021Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples.
10/2020Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors.
8/2020Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers.
1/2020Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes.

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João Lobo Research Topics

Disease

34Neoplasms (Cancer)
11/2022 - 11/2018
16Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
10/2021 - 01/2017
8Renal Cell Carcinoma (Grawitz Tumor)
10/2022 - 01/2020
6Testicular Germ Cell Tumor
10/2021 - 01/2020
6Breast Neoplasms (Breast Cancer)
06/2021 - 01/2019
5Prostatic Neoplasms (Prostate Cancer)
06/2022 - 10/2018
5Carcinogenesis
02/2022 - 12/2019
5Neoplasm Metastasis (Metastasis)
01/2020 - 01/2017
3Urinary Bladder Neoplasms (Bladder Cancer)
02/2022 - 01/2019
2Seminoma
08/2021 - 12/2019
2Testicular Neoplasms (Testicular Cancer)
01/2021 - 01/2020
2Adenocarcinoma
09/2020 - 01/2017
2Lung Neoplasms (Lung Cancer)
04/2020 - 11/2018
1Oxyphilic Adenoma (Oncocytoma)
10/2022
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
12/2021
1B-Cell Lymphoma (Lymphoma, B Cell)
12/2021
1Residual Neoplasm
10/2021
1Teratoma (Teratoid Tumor)
10/2021
1Circulating Neoplastic Cells
03/2021
1Embryonal Carcinoma
01/2021
1Hypoxia (Hypoxemia)
12/2020
1Inflammation (Inflammations)
10/2020
1Villous Adenoma
09/2020
1Metaplasia
09/2020
1Necrosis
08/2020
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2020
1Non-Muscle Invasive Bladder Neoplasms
01/2020
1Disease Progression
11/2019
1Gonadoblastoma
09/2019
1Ascites
01/2019

Drug/Important Bio-Agent (IBA)

19Biomarkers (Surrogate Marker)IBA
02/2022 - 01/2017
8Proteins (Proteins, Gene)FDA Link
01/2022 - 11/2018
7RNA (Ribonucleic Acid)IBA
11/2022 - 11/2018
7MethyltransferasesIBA
06/2022 - 11/2018
7MicroRNAs (MicroRNA)IBA
02/2022 - 01/2019
6Biological ProductsIBA
02/2022 - 03/2020
5Cisplatin (Platino)FDA LinkGeneric
08/2021 - 01/2017
5Phenobarbital (Luminal)FDA Link
12/2020 - 11/2018
4Messenger RNA (mRNA)IBA
02/2022 - 12/2019
4Tumor Biomarkers (Tumor Markers)IBA
01/2022 - 12/2019
4N-methyladenosineIBA
01/2022 - 03/2020
4EnzymesIBA
12/2021 - 12/2018
46-methyladenineIBA
09/2021 - 12/2019
4DNA (Deoxyribonucleic Acid)IBA
01/2021 - 12/2018
3Cadherins (E-Cadherin)IBA
02/2022 - 10/2018
3Histones (Histone)IBA
12/2021 - 11/2018
2trans-sodium crocetinate (crocetin)IBA
10/2022 - 07/2022
2PlatinumIBA
06/2022 - 01/2020
2Androgen Receptors (Androgen Receptor)IBA
01/2022 - 11/2018
2Cell-Free Nucleic AcidsIBA
10/2021 - 03/2021
2Formaldehyde (Formol)FDA Link
12/2019 - 11/2019
2ParaffinIBA
12/2019 - 11/2019
1CytosineIBA
11/2022
1Phosphates (Orthophosphate)IBA
11/2022
1GuanineIBA
11/2022
1Keratins (Keratin)IBA
07/2022
1R-cadherinIBA
02/2022
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
01/2022
1Protein Isoforms (Isoforms)IBA
01/2022
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
10/2021
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
10/2021
1Tretinoin (Retinoic Acid)FDA LinkGeneric
08/2021
1TamoxifenFDA LinkGeneric
06/2021
1Ligases (Synthetase)IBA
06/2021
1Estrogen Receptor Modulators (Antiestrogen)IBA
06/2021
1flavanoneIBA
01/2021
1Keratin-7 (Cytokeratin 7)IBA
01/2021
1Keratin-20 (Cytokeratin 20)IBA
01/2021
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2021
1PanobinostatIBA
10/2020
1Histone Deacetylase InhibitorsIBA
10/2020
1belinostatIBA
10/2020
1Colloids (Colloid)IBA
09/2020
1L-selectin counter-receptorsIBA
08/2020
1beta CateninIBA
08/2020
1Complement System Proteins (Complement)IBA
08/2020
1Tissue Inhibitor of Metalloproteinase-1IBA
06/2020
1human MIRN1293 microRNAIBA
06/2020
1B7-H1 AntigenIBA
04/2020
1Adenosine (Adenocard)FDA LinkGeneric
03/2020
1Histone Deacetylases (Histone Deacetylase)IBA
01/2020
1VimentinIBA
01/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1SirtuinsIBA
01/2020
1Sirtuin 1IBA
01/2020
1Hematoxylin (Haematoxylon)IBA
12/2019
1Eosine Yellowish-(YS) (Eosin)IBA
12/2019
1AntibodiesIBA
11/2019
1Immune Checkpoint ProteinsIBA
10/2019
1Inhibins (Inhibin)IBA
09/2019
1ChromatinIBA
12/2018

Therapy/Procedure

12Therapeutics
06/2022 - 11/2018
4Drug Therapy (Chemotherapy)
06/2022 - 01/2020
2Radiotherapy
12/2020 - 01/2017
2Prostatectomy (Retropubic Prostatectomy)
10/2020 - 01/2017
1Castration
06/2022
1Precision Medicine
06/2022
1Laparotomy
01/2019
1Ovariectomy (Oophorectomy)
01/2019
1Metastasectomy
12/2018